NEW PERSPECTIVES OF GENE THERAPY ON POLYGLUTAMINE SPINOCEREBELLAR ATAXIAS: FROM MOLECULAR TARGETS TO NOVEL NANOVECTORS

New Perspectives of Gene Therapy on Polyglutamine Spinocerebellar Ataxias: From Molecular Targets to Novel Nanovectors

Seven of the most frequent spinocerebellar ataxias (SCAs) are caused by a pathological expansion of a cytosine, adenine and guanine (CAG) trinucleotide repeat located in exonic regions of unrelated genes, which in turn leads guerlain ideal cologne to the synthesis of polyglutamine (polyQ) proteins.PolyQ proteins are prone to aggregate and form intr

read more

Computer hardware for radiologists: Part I

Computers are an integral part of modern radiology practice.They are used in different radiology modalities to acquire, process, and postprocess imaging data.They have had a dramatic influence on contemporary radiology practice.Their impact has extended further with the emergence of Digital Imaging and Communications in Medicine (DICOM), Picture Ar

read more

A New Ken-Ken Puzzle Pattern Based Reconfiguration Technique for Maximum Power Extraction in Partial Shaded Solar PV Array

Solar Photovoltaic array may often be subjected to partial shading, which may lead to uneven row current and creates local maximum power point on the power-voltage characteristics.One of the effective approaches to dilute the concentration of partial shading is the array reconfiguration technique.This study proposes a ken-ken puzzle-based reconfigu

read more